Efecto de suplementos dietéticos en personas con diabetes Tipo II
(A vitamin, mineral, herb dietary supplement effect on blood glucose in uncontrolled Type II diabetic subjects)
Por: Michael J.González, Jorge Miranda-Massari
and Carlos M. Ricart.
InBioMed Project, University of Puerto Rico,
Medical Sciences Campus,
School of Public Health1 and Pharmacy3,
San Juan, PR, Cayey Campus2,
Dept. of Biology, Cayey, PR
En: 1/14/2005
Introduction
We designed a supplement to help with sugar metabolism. Carbo control is an oral synergistic natural formula designed to control the glucose/insulin system. Disturbances in the glucose/insulin system are known to increase diabetes (1), cause hyperglycemia (2), promote hypoglycemia (3), convert sugar to fat (4), and accelerate aging (5), Any nutraceutical capable of helping in the balance of this important metabolic crossroad will be of enormous value. The Carbo Control Formula contains vitamins and minerals: Vitamin C, Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Panthotenic Acid, Choline, Inositol, PABA, Calcium, Phosphorus, Chromium, Vanadium, and Herbs: Garcinia cambogia, Gymnema sylvestre, White Kidney Bean extract and Green Tea. All which have been of some value in helping with glucose/insulin disturbances. This research was done to study the safety and effectiveness of this formula.
Methods
This pilot study was conducted with 15 subjects (8 females, 7 males) with uncontrolled type II diabetes. All patients received two bottles containing 60 tablets of Fattaché Carbo Control Formula. The dose was set at 2 tabs/after lunch and dinner (4 tabs a day). Supplement was taken for a period of a month (30 days). Blood glucose was measured prior to and post supplementation treatment. In addition, a consent release form was signed by the patients. The compliance was 100% during the 30 days of the trail.
Results
The product proved to be non-toxic, with no detrimental side effects and easy to take. The statistical analysis utilized was a Paired Sample T-test to determine statistical significance (p < 0.05). Results were as follows: Blood glucose prior to treatment was 190.55 + 5.11 (mean + standard error) and post treatment 152.75 + 3.32. The result showed a statistically significant difference. Blood sugar glucose was reduce 1/3 with the Carbo Control Formula in hard to respond patients with Type II diabetes.
Discussion
Fattaché Carbo Control Formula is a safe, effective and easy to take product to reduce blood glucose. Its scientific formulation is a combination of vitamins, minerals and herbs that work synergistically to balance the glucose/insulin system. It produced a significant reduction in blood glucose in the experimental group in our study. This result is probably due to metabolic correction by necessary nutrients that are lacking or insufficient in the diabetic metabolism.
Conclusion
Fattaché Carbo Control Formula at a dose of 2 tabs a day after lunch and dinner for a period of 30 days, produced a significant reduction in blood glucose of experimental subjects with uncontrolled diabetes type II.
This preliminary study demonstrated a powerful blood glucose reductive action of the Carbo Control Formula in Type II diabetic patients. A study should be done in hypoglycemic patients, this will be a nice follow up to this extraordinary positive outcome.
An addition possible benefit of the Carbo Control Formulation (reported in 1 patient that had the homocysteine test done) is the reduction of homocysteine, an irritant of the endothelial cells in the wall of the blood vessels that is a risk for cardiovascular disease (6).
References
1. Preuss HG. Effects of glucose/insulin perturbations on aging and chronic disorders of aging: The evidence. J Am Coll Nutr 1977, 16:397-403.
2.
Jebbink RJ, Samson M, Bruijs PP, Bravenboer B, Akkermans LM, Vanberge-Henegoumen GP and Smout AJ. Hyperglycemia induces abnormalities of gastric myoelectric activity in patients with type I diabetes Mellitus. Gastroenterology 1994, 107: 1390-1397.
3.
Kovatchev BP, Cox DJ, Farhy LS, Straume M, Gonder-Frederick L and Clarke WL. Episodes of severe hypoglycemia in type 1 diabetes are preceded and followed within 48 hours of measurable disturbances in blood glucose. J Clin Endocrinol Metab. 2001, 86: 4281-4292.
4.
Moustaid M, Jones BH and Taylor JW. Insulin increases lipogenic enzyme activity in human adipocytes in primary culture. J Nutr 1996, 126: 860-870.
5.
Fukagawa NK, Li M, Liang P, Russell JC, Sobel BE and Abshner PM. Aging and high concentration of glucose potentiate injury to Mitochondial DNA. Free Rad Biol Med 1999, 27:1437-1443.
6.
Jacobsen DW. Homocysteine and Vitamins in cardiovascular disease. Clin Chem 1998, 44:1833-1843
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